Confidential
Best Medical Technology (25) |Download All
| Company | Product | Submission | Cato T. LAURENCIN |
Steven LESTER |
Total |
Aggregated Vote |
Vote
1 Most favorable
5 Least favorable
1=most favorable; 5=least favorable
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|---|---|---|---|---|---|---|---|
| Alcon | TOTAL30® Soft Contact Lenses |
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| Medtronic | MiniMed™ 780G system |
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| Abbott | TriClip™ G4 System |
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| RefleXion Medical | RefleXion® X1 with SCINTIX® biology-guided radiotherapy |
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| Smith & Nephew, Inc. | CORI Surgical System |
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| Edwards Lifesciences | Edwards EVOQUE Transcatheter Tricuspid Valve Replacement System |
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| Medtronic | Symplicity Spyral™ Renal Denervation System |
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| Impulse Dynamics | Optimizer® Smart Mini System |
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| Abbott | AVEIR™ Dual Chamber (DR) Leadless Pacemaker System |
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| Medtronic | Inceptiv™ Closed-Loop Spinal Cord Stimulator |
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| ENDOLOGIX LLC | DETOUR System |
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| Edwards Lifesciences | Edwards SAPIEN 3 Ultra RESILIA Transcatheter Aortic Heart Valve |
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| Terumo Aortic | Thoraflex Hybrid™ |
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| Polarean | XENOVIEW HPX System |
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| Perspectum | CoverScan |
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| Guardant Health | Guardant360® CDx |
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| Cresilon | TRAUMAGEL® |
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| BioProtect | BioProtect Balloon |
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| Establishment Labs Holdings Inc. | Motiva Flora Tissue Expander |
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| Body Vision Medical | LungVision |
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| Beyond Air, Inc. | LungFit® PH |
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| bioMérieux | BIOFIRE® SPOTFIRE® System and BIOFIRE® SPOTFIRE® Respiratory/Sore Throat (R/ST) Panel |
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| Abbott | Esprit™ BTK Everolimus Eluting Resorbable Scaffold System (Esprit™ BTK System) |
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| OUR United | TaiChiPro |
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| Boston Scientific | FarapulseTM |
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b6cohen@galienfoundation.org
PENNY's Comments:
For this category, I weighed feasibility along with patient outcomes and societal impact more heavily than the other categories. This resulted in a top three of Evoque tricuspid system, Guardant360 biomarkers, and BioFire diagnostics, all of which are clinically relevant and well validated. Next is LungFit PH just ahead of Symplicity Spyral based on feasibility of execution, with the remaining candidates falling lower because of limited evidence on outcomes.
Best Digital Health Solution (25) |Download All
| Company | Product | Submission | Junaid Bajwa |
Sally Ann Frank |
Sachin Nanavati |
Jay Rajda |
MaryAnne Rizk |
Steve Rosenberg |
Daniel Vial |
Total |
Aggregated Vote |
Vote
1 Most favorable
5 Least favorable
1=most favorable; 5=least favorable
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Recursion | Recursion Operating System (OS): end-to-end AI-driven drug discovery and development platform |
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| TECHMEDO Inc. | Healthcare Operating System |
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| Empatica | Empatica Health Monitoring Platform |
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| Aptar Digital Health | Migraine Buddy's Weather and Trigger Advanced Reports |
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| Clinical ink | GlucoseReady (TM) |
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| University of Rochester - Wilmot Cancer Institute | University of Rochester - Wilmot Cancer Institute's Hyperion |
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| Patientory, Inc. | Patientory Digital Health Data Wallet |
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| Abbott | NeuroSphere™ Virtual Clinic |
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| Mymee | Mymee’s product is a proprietary personalized trial & care platform for rheumatic autoimmune patients who can no longer control disease flares with prescription therapies. |
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| MPA | MyPsychAdmin |
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| AdhereTech | Aidia System |
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| Evinova | Evinova Unified Trial Solution |
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| Cleerly | Cleerly LABS |
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| Future Doctor Inc | MedGPT - AI Digital Twin of Doctors |
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| Wheel | Wheel Horizon |
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| ŌURA | Oura Ring 4 |
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| Helfie AI | Helfie AI |
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| RapidAI | Rapid Aneurysm |
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| All4Cure, Inc. | All4Cure Platform |
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| Otsuka Precision Health | Rejoyn |
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| First Ascent Biomedical Inc | xDRIVE/DxPP |
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| NeuraLight | NeuraLight platform |
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| WARD 24/7 | WARD Clinical Support System (WARD-CSS) |
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| Beaconcure | Verify |
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| DNAnexus + Boehringer Ingelheim Joint Submission | Project PRISM/Project CRYPTx |
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b6cohen@galienfoundation.org
PENNY's Comments:
For this category, Recursion ranks highest because of the potential to change drug discovery at
scale. Rejoyn and NeuroSphere are already delivering clinical benefits but in narrower
therapeutic areas. Oura Ring is a valuable consumer wellness tool but has less direct impact
on patient outcomes today.
Best Incubator, Accelerator, Equity (12) |Download All
| Company | Product | Submission | Gil BASHE |
Ron COHEN |
Jamey EDWARDS |
Amir KALALI |
Michelle LONGMIRE |
Julien de Salaberry |
Total |
Aggregated Vote |
Vote
1 Most favorable
5 Least favorable
1=most favorable; 5=least favorable
|
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cross-Border Impact Ventures | Women's and Children's Health Technology Fund |
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| McGill Dobson Centre for Entrepreneurship | McGill Dobson Centre for Entrepreneurship |
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| EIT Health | EIT Health Accelerator |
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| MATTER | SMILE Health |
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| Cube Labs | Cube Labs |
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| Mayo Foundation for Medical Education and Research | MAYO CLINIC AND ARIZONA STATE U. ALLIANCE for HEALTH CARE ACCELERATOR |
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| OROT - CIUSS Montreal | OROT - Connected Health Incubator, CIUSSS West Central (Montréal) |
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| Endless Frontier Labs - New York University Stern School of Business | Endless Frontier Labs |
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| Calibr-Skaggs Institute for Innovative Medicines | Calibr-Skaggs Drug Accelerator |
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| Cornell University | Center for Life Science Ventures |
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| Nucleate Bio, Inc. | Nucleate Activator |
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| Avant Bio | Avant Bio Fund II LP |
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b6cohen@galienfoundation.org
PENNY's Comments:
For Best Incubator, I ranked Calibr highest because it has the most direct, measurable pathway
to improving patient outcomes. Unlike other accelerators that support early ventures, Calibr
operates as a translational engine, with more than 10 programs in clinical trials. While EIT
Health and the others provide highly valuable ecosystem support, I perceive that Calibr has
greater potential to generate tangible therapies with high patient impact.
Best Startup - MedTech / Digital Health ( 21 )
| Company | Product | Submission | Elaine Brennan |
Michael Langer |
Jonathan Marchado |
Total |
Aggregated Vote |
Vote
1 Most favorable
5 Least favorable
1=most favorable; 5=least favorable
|
|---|---|---|---|---|---|---|---|---|
| Bloqcube Inc. |
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| Ganymed Robotics | Ganymed Robotics |
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| Click Therapeutics | Prescription Digital Therapeutics |
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| SIMEDYS | SIMEDYS |
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| Canary Medical | Canary Medical |
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| Actipulse Neuroscience | Actipulse |
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| Manus Neurodynamica US |
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| MediVIE Tech |
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| Adaptilens, Inc. |
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| XaTek Inc. |
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| Navigation Sciences, Inc. |
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| Zest Health | Zest Health |
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| magAssist Co., Ltd. |
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| Kapsule |
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| REGEnLIFE |
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| Gleamer |
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| SmartBiotic |
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| Imaginostics, Inc. |
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| Vocxi Health |
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| Esperto Medical, Inc. |
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| Resuscitec GmbH |
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b6cohen@galienfoundation.org
PENNY's Comments:
Again, I weighted feasibility alongside patient outcomes and societal impact as the most
important attributes. Kapsule emerges as the most robust startup already scaling health data
infrastructure. Resuscitec and Manu follow, each having strong outcome potential with early
regulatory and/or commercial traction. XaTek has a feasible diagnostic innovation and
REGEnLIFE has big potential for impact despite some feasibility risks. The others rank lower
with more limited progress/execution.
Best Startup - BioTech ( 32 )
| Company | Product | Submission | Steve Eror |
Detlev Mennerich |
Leighanne OH |
Total |
Aggregated Vote |
Vote
1 Most favorable
5 Least favorable
1=most favorable; 5=least favorable
|
|---|---|---|---|---|---|---|---|---|
| ViCardia Therapeutics, Inc. |
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| Micron Biomedical, Inc. |
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| Duo Oncology | Duo Oncology |
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| BigHat Biosciences | Milliner |
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| Qubit Pharmaceuticals | Qubit Pharmaceuticals |
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| Immunis, Inc. |
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| TargED Biopharmaceuticals B.V. |
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| ALGA BIOLOGICS | ALGA BIOLOGICS |
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| Hope Medicine |
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| SURGE Therapeutics |
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| Libera Bio S.L. |
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| Insilico Medicine |
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| Bitterroot Bio |
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| Ascidian Therapeutics |
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| ADVANCED BIODESIGN |
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| Nona Biosciences |
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| Shenzhen ReeToo Biotechnology Co., Ltd. |
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| CUTISS AG |
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| LEAF4Life, Inc. |
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| Paradigm Therapeutics |
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| Seismic Therapeutic |
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| Strand Therapeutics |
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| SFA Therapeutics, Inc. |
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| Quercis |
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| Geneos Therapeutics | GNOS-PV02+INO-9012 followed by intradermal electroporation. Personalized Therapeutic Cancer Vaccine |
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| Gatehouse Bio, Inc. |
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| SEED Therapeutics |
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| Turbine Simulated Cell Technologies Limited |
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| Dren Bio |
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| Nospharma |
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| Mammoth Biosciences |
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| Intrepid Labs |
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b6cohen@galienfoundation.org
PENNY's Comments:
When considering these companies, I prioritized feasibility and near-term ability to deliver
patient outcomes and favorable benefit to society, while still recognizing long-term potential.
Thus, Dren and CUTISS rise to the top (essentially a tie) with Mammoth close behind with
higher risk and a longer horizon.