U.S.A.
2020 Nominees
| Product | Company | Therapeutic Area & Indication |
|---|---|---|
| Abbott’s MitraClip™ Transcatheter Mitral Valve Repair System | Abbott | Mitral valve regurgitation Read more |
| Venovo™ Venous Stent System | Becton, Dickinson and Company | Iliofemoral venous occlusive circulation disease Read more |
| PK Papyrus Covered Coronary Stent System | Biotronik | Coronary artery perforations Read more |
| AXIOS™ Stent and Electrocautery Enhanced Delivery System | Boston Scientific Corporation | Trans-gastro or trans-duodenal repair of pancreatic pseudocysts and necrosis Read more |
| HeartLogic™ | Boston Scientific Corporation | Cardiovascular Read more |
| SENTINEL | Boston Scientific Corporation | Endovascular disease debris repair Read more |
| Cala Trio™ | Cala Health | Neuroscience Read more |
| CUSTOMFLEX® ARTIFICIALIRIS | Clinical Research Consultants, Inc. and HumanOptics AG | Ophthalmology Read more |
| Edwards SAPIEN 3 Ultra™ Transcatheter Heart Valve System | Edwards Lifesciences | Aortic stenosis Read more |
| INSPIRIS RESILIA™ Aortic Valve | Edwards Lifesciences | Aortic valve replacement Read more |
| Magtrace® and Sentimag® Magnetic Localization System | Endomag | Oncology Read more |
| iStent inject® W | Glaukos Corporation | Ophthalmology/open-angle glaucoma Read more |
| CCM® Therapy for Heart Failure | Impulse Dynamics | Congestive heart failure Read more |
| Implantable System for Remodulin® | Medtronic | Pulmonary arterial hypertension Read more |
| reSET® and reSET-O® | Pear Therapeutics | Substance use disorder Read more |
| Zephyr Endobronchial Valve System® | Pulmonx Corporation | Emphysema Read more |
| The GentleWave® System | Sonendo® | Root canal treatment Read more |
| ProAir® Digihaler™ | Teva Pharmaceutical Industries | Pulmonary respiratory disease Read more |
| Product | Company | Therapeutic Area & Indication |
|---|---|---|
| Tegsedi® | Akcea Therapeutics and Ionis Pharmaceuticals | Polyneuropathy caused by hereditary transthyretin-amyloidosis (hATTR) in adults. Read more |
| ULTOMIRIS® (ravulizumab-cwvz) | Alexion Pharmaceuticals, Inc | Paroxysmal nocturnal hemoglobinuria (PNH) that destroys red blood cells in adults Read more |
| GIVLAARI® | Alnylam Pharmaceuticals | Acute hepatic porphyria (AHP) linked to production of toxic porphyrin molecules in the bloodstream in adults Read more |
| ONPATTRO® | Alnylam Pharmaceuticals | Polyneuropathy caused by hATTR amyloidosis leading to loss of nerve and organ function Read more |
| Aimovig® | Amgen | CGRP receptor blocker to treat chronic migraine Read more |
| EVENITY® | Amgen | Osteoporosis in post-menopausal women at high risk of bone fracture Read more |
| GALAFOLD® | Amicus Therapeutics, Inc. | Oral drug for treatment of Fabry Disease through repair of gene-induced enzyme deficiencies that lead to organ failures, stroke and early death in adults Read more |
| Palynziq® (pegvaliase-pqpz) injection | BioMarin Pharmaceutical, Inc. | Lowers blood levels of phenylalanine, an amino acid that causes PKU (phenylketoneuria) leading to brain damage and seizures beginning in infancy Read more |
| ENHERTU® | Daiichi Sankyo & AstraZeneca | Treatment of unresectable or metastatic HER2 positive breast cancer Read more |
| OXERVATE® | Dompé U.S. Inc. | Recombinant human growth factor to treat neurotrophic keratitis, a rare condition affecting the eye cornea Read more |
| Emgality® | Eli Lilly and Company | Once a month CGRP antibody preventive treatment for adult migraine Read more |
| Hemlibra® | Genentech Inc. | Reduce or prevent bleeding episodes in adults and children with hemophilia A, with or without factor-VIII inhibitors Read more |
| Polivy™ | Genentech, a member of the Roche Group | Antibody drug conjugate for treatment of diffuse large B-cell lymphoma Read more |
| Oxbryta® | Global Blood Therapeutics, Inc. | Prevents inherited propensity for the hemoglobin polymerization that causes sickle cell disease Read more |
| TREMFYA® (guselkumab) | Janssen Biotech, Inc. | Medium to severe plaque psoriasis in adults Read more |
| LILETTA® | Medicines360 | IUD to prevent pregnancy through timed release of hormone levonorgestrel Read more |
| ERVEBO® | Merck & Co., Inc | First preventive vaccine against the disease caused by the Zaire ebolavirus in adults Read more |
| Zolgensma® (onasemnogene abeparvovec-xioi) | Novartis Gene Therapies | One-time gene replacement therapy for children under age 2 with spinal muscular atrophy Read more |
| Rybelsus® | Novo Nordisk | GLP-1 agonist treatment to control blood sugar in adults with Type-II diabetes Read more |
| VYNDAQEL® (tafamidis meglumine) | Pfizer Inc. | For cardiomyopathy associated with transthyretin-mediated amyloidosis (ATTR-CM) to reduce cardiovascular mortality and related hospitalizations Read more |
| Andexxa® | Portola Pharmaceuticals, Inc. | Reversal of medicine-specific, anticoagulant-based, and life-threatening bleeding events Read more |
| Dupixent® (dupilumab) | Regeneron and Sanofi | Single dose pre-filled pen technology to treat adults and adolescents with atopic dermatitis (eczema), asthma and rhinosinusitis with nasal polyposis Read more |
| Cablivi® | Sanofi | Nanobody to treat adult acquired thrombotic thrombocytopenic purpura (aTTP), a rare blood disorder Read more |
| TAKHZYRO® | Takeda Pharmaceutical Company Limited | Treatment for hereditary angioedema (HAE) in adults Read more |
| Product | Company | Therapeutic Area & Indication |
|---|---|---|
| RINVOQ® | AbbVie Inc. | JAK (janus kinase) inhibitor that blocks inflammation of moderate to severe rheumatoid arthritis (RA) in patients who don’t benefit from existing treatments Read more |
| Adhansia XR® | Adlon Therapeutics L.P., a subsidiary of Purdue Pharma L.P. | Central nervous system stimulant to treat attention deficit hyperactivity disorder (ADHD) in people age six and older Read more |
| Lutathera | Advanced Accelerator Applicati | Radioactive isotope treatment for cancerous neuroendocrine tumors affecting the pancreas or gastrointestinal tract Read more |
| XOSPATA® | Astellas Pharma | Tyrosine kinase inhibitor for adults with relapsed or refractory acute myeloid leukemia (AML) with the tyrosine kinase-3 gene mutation Read more |
| NUBEQA® | Bayer U.S., LLC | For patients with non-metastatic castration-resistant prostate cancer Read more |
| VITRAKVI® | Bayer U.S., LLC | Larotrectinib (trade name: VITRAKVI®) is a first-in-class tropomyosin receptor kinase (TRK) inhibitor to treat tumors that have a neurotrophic receptor tyrosine kinase (NTRK) gene fusion. Read more |
| REYVOW (lasmiditan) | Eli Lilly and Company | A serotonin (5-HT) 1F receptor agonist indicated for the acute treatment of migraine with or without aura in adults Read more |
| Olumiant® | Eli Lilly and Company | JAK inhibitor for treatment of Rheumatoid Arthritis in patients who fail to benefit from existing TNF alpha inhibitor therapies Read more |
| Rozlytrek™ | Genentech, a member of the Roche Group | First “tumor agnostic” treatment with biomarkers to specifically target ROS-1 positive metastatic non-small cell lung cancer (NSCLC) as well as other NTRK gene fusion positive solid tumors Read more |
| Epidiolex® | GW Pharmaceuticals plc & Greenwich Biosciences Inc. | Reduction of seizures associated with Leno-Gastaut Syndrome (LGS), Dravet Syndrome and Tuberous Sclerosis Complex (TSC) in adults and infant children Read more |
| ERLEADA® | Janssen Biotech, Inc. | Non‑steroidal selective antagonist of the androgen receptor to treat adults with metastatic castration-sensitive prostate cancer and patients with non-metastatic castration-resistant prostate cancer who are at high risk for developing metastasis Read more |
| BALVERSA® | Janssen Biotech, Inc. | Kinase inhibitor to treat adults with advanced or metastatic urothelial cancers that are susceptible to FGFR2 or FGFR3 mutations or have proven resistant to chemotherapy Read more |
| XPOVIO® | Karyopharm Therapeutics Inc. | Treatment of relapsed/refractory (RR) multiple myeloma and RR diffuse large B-cell lymphoma Read more |
| Moxidectin | Medicines Development for Global Health & TDR | New treatment for onchocerciasis (river blindness) demonstrating superiority over ivermectin, the current standard of care against this major neglected infectious disease prevalent in developing countries. Read more |
| RECARBRIO™ | Merck & Co., Inc | Combination anti-bacterial for adults with complicated urinary tract infections and complicated intra-abdominal infections Read more |
| Piqray® (alpelisib) | Novartis Pharmaceuticals Corporation | Treatment of advanced or metastatic breast cancer with PIK3CA gene mutation Read more |
| Adakveo® (crizanlizumab-tmca) | Novartis Pharmaceuticals Corporation | Treatment to lower frequency of recurrent vaso-occlusive crises associated with severe vascular system pain for conditions like sickle cell anemia Read more |
| Entresto® (sacubitril/valsartan) | Novartis Pharmaceuticals Corporation | Reduce hospitalizations and deaths in adults with chronic heart failure through improvement in the heart’s ability to pump blood to the body Read more |
| LORBRENA® | Pfizer Inc. | For patients with anaplastic lymphoma kinase (ALK) positive metastatic non-small cell lung cancer (NSCLC) in cases where previous ALK inhibitors have failed Read more |
| Annovera™ | Population Council and TherapeuticsMD | Novel hormonal contraceptive vaginal ring that prevents ovulation and pregnancy over a full-year cycle of use Read more |
| ASPARLAS | Servier Pharmaceuticals | Component therapy of a multi-agent chemotherapy regimen for treatment of acute lymphoblastic leukemia (ALL) in patients 21 years of age or younger Read more |
| TPOXX® | SIGA Technologies, Inc. | First drug with an indication for treatment of smallpox in humans in the event of its use as a bioweapon and public health emergency Read more |
| Gamifant® | Sobi, Inc. | First treatment for infants/adults with primary haemophagocytic lymphohistiocytosis (HLH), an ultra-rare immune disorder that leads to severe inflammation, infections, bleeding, organ failures and early death. Read more |
| Pretomanid | TB Alliance | A nitroimidazole drug, one of a class of novel anti-bacterials and approved as a combination with two other drugs for use in patients with highly drug-resistant pulmonary tuberculosis (TB). Read more |
| YUPELRI® (revefenacin) Inhalation Solution | Theravance Biopharma, Inc. | Anticholinergic to treat chronic obstructive pulmonary disease (COPD), including emphysema and chronic bronchitis Read more |